Defective cell culture questioned the results of cancer research

Scientists from the Netherlands, questioned the results of numerous scientific studies of cancer, according to MedPage Today. According to experts at the University of Erasmus of Rotterdam (Erasmus University Rotterdam), for these studies were used inappropriate cell culture. The researchers studied the genome of 13 of the 14 currently used in cell cultures of esophageal adenocarcinoma. It turned out that the three cultures (SEG-1, BIC-1 and SK-GT-5) contained a cell tumor of the lung, intestine and stomach.

According to the Dutch experts, the results of this study formed the basis of clinical trials of drugs. In addition, the results of this work were written over a hundred scientific articles, as well as eleven issued patents and three grants for further research in this area.

In addition, scientists from Rotterdam consider it necessary to revise the rules of appointment of the drug, sorafenib, used in the treatment of esophageal cancer, since studies of its effectiveness have been used in cells of other types of tumors.

Representative of the British Health Protection Agency (Health Protection Agency), which owns a large collection of cell cultures, said that the problem of the use of inappropriate cell research arose more than 20 years ago. He noted that the organization's website published a growing list of cell cultures, certain incorrect or contaminated by cells of another type.

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